Objectives: We aimed to present a case of Sheehan's syndrome associated with Glanzmann's thrombasthenia. Case Report: A 41-year-old-woman presented with hemorrhagic diathesis needed blood transfusions occasionally during her life-time. In the course of her second delivery, four units of whole blood transfusion were required to control profuse uterine bleeding and her hemodynamic status. During postpartum period, she was not able to lactate and her menstrual periods did not return. Her hormonal pro. le revealed gonadotropin, TSH and prolactin deficiencies. Conclusion: According to our knowledge, this is the first case report of hypopituitarism developed after delivery in association with Glanzmann's thromboasthenia-induced severe uterine hemorrhage.