Background and Objectives: Acute aortic dissection (AAD) is a life-threatening condition resulting from the separation of the aortic intima and media layers. Prompt intervention in AAD is crucial to improving patient survival and reducing complications. This retrospective study aimed to investigate the correlation between symptom onset to diagnosis interval and subsequent mortality and morbidity in AAD patients.<br /> Methods: A retrospective analysis was conducted on 32 AAD patients presenting to the emergency department between January 2015 and June 2018. Patients were divided into 2 groups based on the time interval between diagnosis and intervention: Group 1 (diagnosis to operation <= 4 hours) and Group 2 (> 4 hours). Results: The mean age of patients was 57.3 +/- 10.2 years. Group 1 included 32 males and 12 females, while Group 2 consisted of 16 males and 4 females, with mortality rates of 18.1% and 50%, respectively (P=0.046). Conclusion: AAD is associated with high morbidity and mortality rates, emphasizing the importance of timely diagnosis and treatment. This study underscores the vital role of rapid diagnosis and intervention in reducing mortality for AAD patients, emphasizing the need for efficient diagnostic protocols in emergency settings.