Objectives: This study aims to examine nurses' acceptance of Mobile Health Applications.,Methods: This cross-sectional study was conducted with 321 nurses in a health practices and research center between March-July of 2020. Data collection instruments were Personal Data Form and Mobile Applications Acceptance Model.,Results: In this study, 97.2% of the nurses believed that mobile health applications should be used more in hospitals. The total mean score of the nurses on the Mobile Applications Acceptance Model (MAAM) was 124.69 +/- 15.98. Nurses under the age of 30, those who worked in intensive care units, and those who owned a mobile device exhibited higher total mean scores on the MAAM (p<0.05). The MAAM total mean scores were higher among those who thought Mobile Health Applications should be made more widespread (p<0.04), who felt that Mobile Health Applications were effective in accessing individual health data (p<0.001), who felt that using Mobile Health Applications were easy (p=0.02), who believed that using Mobile Health Applications helped patients access health services without having to go to the hospital (p<0.001), and who wanted to help patients obtain health services without going to the hospital (p<0.001).,Conclusion: Nurses' level of mobile health applications acceptance in terms of using mobile applications was high in our study. Most of the nurses expressed positive views on the use of mobile applications in the hospital setting.