Two novel triterpene glycosides, paphlagonoside A (1) and B (2), were characterised as 28-O-[-D-glucopyranosyl(1 2)--L-arabinopyranosyl(1 4)--D-glucopyranosyl]-hederagenin (1) and 28-O-[-D-xylopyranosyl(1 4)--L-rhamnopyranosyl(1 3)--D-xylopyranosyl (1 6)--D-glucopyranosyl(1 2)--D-glucopyranosyl]-hederagenin (2) from Cephalaria paphlagonica (Dipsacaceae). In addition to these, a common natural product (hederagenin) (3) was also isolated. The structures of all compounds were identified by spectroscopic and chemical methods. The antimicrobial and antioxidant activities of the plant extracts were examined by MIC and DPPH activity methods, respectively.