This work aimed to investigate the production of Sm-151 and Eu-152,Eu-154,Eu-155 on natural Nd and Sm targets via particle accelerator because these radionuclides have the potential for use in nuclear battery technology such as betavoltaic batteries and radioisotope thermoelectric generators. Therefore, this work estimated cross-section curves for proton, deuteron, triton, helium-3, and alpha particles induced reactions in the energy range E-particle = 100 -> 1 MeV. The activities and products of yield were simulated for all reaction processes under selected conditions, the particle beam current of 1 mA and the irradiation time of 24 h. Moreover, to understand the formations of Sm-151 and Eu-152,Eu-154,Eu-155 in the reaction processes, the appropriate energy region of the reactions by calculating the integral yield curves were determined. Based on the obtained results, determination of suitable targets, energy regions, and reaction processes were discussed by this work.