Abstract
Objective: In this study, we investigated whether serum androgen levels and endometrial thickness differed in obese and non-obese women.,Material and Methods: Thirtytwo non-obese (BMI <30) and 48 obese ( BMI 30) women were enrolled. Blood samples were analyzed for testosterone, free testosterone, androstenedione, DHEAS, and SHBG, and transvaginal ultrasonography was performed.,Results: Obese women had significantly higher free testosterone and endometrial thickness and significantly lower SHBG. Eight of 17 women with endometrial thickness >5 mm had significant pathology.,Conclusion: These results suggest that obesity may be a risk factor for endometrial carcinoma and other pathologies in post-menopausal women through an action on androgen concentrations.
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Kapsamı
Uluslararası
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Type
Hakemli
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Index info
WOS.ESCI
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Language
English
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Article Type
None
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Keywords
Serum androgene endometrial thickness obesity postmenopause