Abstract
OBJECTIVES,This study examined the frequency of chronic lymphocytic thyroiditis (CLT) in thyroid papillary carcinomas (TPC) and the relationship between the presence of tumor-infiltrating lymphocytes (TIL) and CLT.,METHODS,The study included 61 TPC cases. In each case, the presence of the lymphocyte infiltration in the tumor tissue and nonneoplastic parenchyma was graded semi-quantitatively using a scale of 0 to 3. The cases were classified in two groups, TPC including CLT (Group I) and TPC not including CLT (Group II).,RESULTS,CLT was detected in 26.3% (Group I) of the TPCs and TIL was observed in 77% of the Group I cases; no lymphoid infiltration compatible with TIL was detected in Group II. A significant difference was observed in the TIL density between Groups I and II.,CONCLUSION,CLT is a frequent finding in TPC, and the presence of TIL is related to CLT.
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Kapsamı
Uluslararası
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Type
Hakemli
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Index info
WOS.ESCI
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Language
Turkish
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Article Type
None
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Keywords
Lymphocytic thyroiditis papillary carcinoma thyroid tumor-infiltrating lymphocytes