In this study sulfur dioxide adsorption and rate were investigated on molecular sieve 5A zeolite in a packed bed system at 473 K. The experimental adsorption isotherms were compared with Langmuir, Freundlich, and Dubinin-Radushkevitch-Kaganer (DRK) adsorption isotherm models. The simple Langmuir and the Freundlich models provided a better description of sulfur dioxide sorption on molecular sieve 5A zeolite, so that a selective surface adsorption mechanism for adsorption of sulfur dioxide on molecular sieve 5A zeolite can be suggested. The breakthrough behavior for sulfur dioxide adsorption on molecular sieve 5A was also investigated in this study. The experimental breakthrough curves were compared with deactivation models proposed by Orbey et al., and the recent models of Suyadal et al. and Yasyerli et al. The deactivation models were found to give good agreement with the experimental results.